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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4444f0cb758962e8c75d18bc8fb9442a6e4d74467929542592642a1f1c34443' 
  AND token = 'YdTyU0/gpkYHPagIFO/EnVCsLYUngvL9kOa7nD4D2Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}