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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0157505282856223115498dd236c72b5cf11d8015dde2b2dc0f4c624fa2ec01' 
  AND token = 'FWB1X48yXDe/7POtuL8Sm6A4FNLFaggNjkrxeuMv7OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}