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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b250e726cd22f39d3b2b4f480f81fd1da054e65f338ef80845b9821e24c2f70' 
  AND token = 'cPmfW5HDblBz32p8kqyAjhsY27J2cZ/L5y8a9Rneqjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}