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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c149b593d4ba13718a2c92d139b84b7d69819df5141793ca64aa4f0c0558eb94' 
  AND token = 'd6lb/dAIbPIcMVxvZoi0I6vIKabnIOAWlzfPdKxjcYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}