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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495a58391529bed0cfb5a5e19400945619d7d6cc449c0e93cff46bbf381a65f0' 
  AND token = 'SZqHDk0jc19mCv6575DQsmpHRiqQeVouJeIJv2WBD7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}