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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5079a2851e616497005cfb4b0eb04c25004d169bd708bc688aa0852be9ff12' 
  AND token = 'DAqJhdFnUtNJfzD+g+q7Kgejabjc2AFskUthnd1PxJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}