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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65107892c1a787df69301fd33ed82a0369d9f2ab776ce47d4f7ce9efeeaa3af2' 
  AND token = 'MQ6d5snHWpYMw3LASi1qJ5lhgIl8HJE1R2RFcfs6/Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}