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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cc0ece3ae163cdd10dd03c7362e4132656114291fdd089c59ecc4d7ae34e83' 
  AND token = 'E9aEdSDN+7NqBO1UppOhA8cNE5zam6c3cFoV4mDPcvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}