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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191e4b50eff01a60a467fb213a82ca7519a927c5e61667b19578bbade34b0a5a' 
  AND token = '1PzWnuEPou1BFMp/q7DR27EDq+EOyygRGJR4vXqZvLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}