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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6d8f329462e5e07e759f790d5a2c8b49f148c9abf85011f3d2526609dce0f6' 
  AND token = 'Y5CLRsY8AfPs5NCWtQSn6aECNdK17AdH1LPXbJAR+ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}