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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3083bfa55f0c35a306f5c8caa2e4df20656e5033a1b2a93fe7283f8e6847a2' 
  AND token = '+uFc00NmBzqetq06nWocQYeq5s8a7xPS0oLfoytFflw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}