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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a331d986f9638a52f6fe7f1cabc4f6b4a27a5662e8bf397def5b4faa8e6714b7' 
  AND token = 'r4UCGRP8WR2OSEpFsURPM85IEDKe0Ut/FelS6JJc3tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}