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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7294dff42c2e299a2148c70ca96b25db02c54d33560d6321887196272f13fd42' 
  AND token = 'PTIWz3Vl9X0TFTN2VjjofBE7PXaCUELAv7ogRNNMf7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}