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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bd1922e1c138170f868da3b4eb16c2c7178d48b0513fe20c180a3e39c2f1da' 
  AND token = 'jdTECelir97kxe8qkaZWTX2b9tJFft0dh7QTP6NvVmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}