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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d836dd05e6a548e225e5be7ff08f583f0128799f86c03c25a5e66b7842e1c3' 
  AND token = 'XGeG2+326SU6TAtx5P/ZZTIO1CZLdMVVmxgkBOlC6sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}