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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cd0496b32a56edf619db96f576039bea84298e4d6f3b0e33e235dabb8bfb01' 
  AND token = 'zp6k6YKv7r8kFzwIzWk+vUEDQZ77o9R5N5yN9jw1erQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}