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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46dde55e5c5a62cbf9210e7057ef6b1d03427d99e7db1d6308a0069ef01b882' 
  AND token = 'l6ILvuszautYa3KhaXWG47NH1iJiQWG+i3kFBSkaJOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}