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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c007b45d24c03bbd7a6fd7785c502fd0dad92475f4bdc8e6c74afdcfa836a551' 
  AND token = 'YTy5UigFRYXX4Cn3D4ABwhx56fA7vB2DOhnwWT3mLOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}