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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0251e60885a0a96e7280d5700d98c0b0de9818dad362ccca295647e7dd1a292' 
  AND token = '+I4YZX29rLHOwFX2VXcXkOBLmY6aEiAiBZL8PEwcxMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}