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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd005727dc721afca47f5a1383c3a217ad8f8daa0e879272232e7a12eb58afca6' 
  AND token = 'n7mmFM42hsfy2m39e1EVEd3DtOXERdhjmqNPe0yvx64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}