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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41401f345b5dfdeeb5f3d85eadafc480578cf3e43e66ccdd8c5badc4e7861937' 
  AND token = 'ku+O+Y5uMfK553CPcq4DutjQN+m3Ac7OMgKCBaroFWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}