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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec5f659304e9f2062145629dd03068ad30df02739ea90d0b08d1a2743f80e5d' 
  AND token = '2ZHXZLC2Kex/kq0jLr4Zmynxs6sseNzI51mJ3XdMVBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}