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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ab6bb0fd29bcc58fbaa4b6c22fac2a86556c2d521f627b5c526e89af7e2ba6' 
  AND token = 'QoNeGPpJaeC+tI8GyDnpJ88DU+VmTZVR81zsC4ePL+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}