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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b2be5af72143322a5a5905b7b54049d94ae218e644f112a0224d078f4e9167' 
  AND token = 's0RuDV1FxXOhgP4VKeN5vbpOWlIr8yZwijn1NrxR9O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}