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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e74dd7f94aab18f733237f12085b12011ef9e4ed3fd5e031060289b7fb2d66' 
  AND token = '3vWcJ+jDnq8tfnQJKOcD27FFaYu0TnzuR2+XCIxbFns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}