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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c35067b32af294849b21a5fa01edcf98b29f24877eaf292de209e65cc571f10' 
  AND token = 'RTZ9kRb5/dN/RXP8MA5ssZ0u81nTw6XdPuuD+Aw144E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}