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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495f242bee27e9c0265ea0eec37bc91db2c071fd93469b962e4fa92c9518e583' 
  AND token = 'gej2prQCUeinvun2ZXFaU96UwdXmgPNReSfW4qjbiI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}