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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d6aa2938cca500b5c2e47391ddfad8b6321fe5e1be4097cb05bf0ee97bd547' 
  AND token = 'YOU0dLF0hpc20DvoxaJj+LzZEvHj8gNaOw05oKRItXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}