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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d479ac20c9123f2205f1ac3fcf2e7d63fb8e67468fb003783e63466ae0129ec' 
  AND token = 'vVj8DTL5eCjno5CQmPXTt4cwa0ZO8O/9ImxxR5TgmzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}