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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c5c004a41c82089f37c76219c74569d06a4e22e6925a0ab7df820cb57a0ac3' 
  AND token = 'iKL/gexbTLaciiBW6/rrtHbiMlOeLLW8ba+tieOXj+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}