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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106afa27d215e141b6748f35904195aea7cfe8439fedec30d67b4b5e65ca2235' 
  AND token = 'WSrqNY0k4+5yE49doekbjN5FbexSZSxP5CirG0qxIFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}