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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce46d196414fd2230aae357b3a313b4083c8be6ced88a8acac38095570e74870' 
  AND token = 'vgxS/IA3Lk9N2FdYLKsAfHhVa4ooVTo27nY+M3SuZcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}