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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4ac3a793ecb61ef13aae696246ca58454c76ba6e934cc000d500cb07513298' 
  AND token = 'dukbMZIYEVIK+evn7pi2xXhqy4wDA4Z0Vxqahqcq9Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}