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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a1f3c34296c46ae2e90a928bf800575f3a53cf32943e5026a5cccbb770bec7' 
  AND token = 'u+AAaRdu+e+QW+yOUUpgoRgWOZ74ds+FPZqfyPgdJfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}