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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50ffd812c6bc5ba9f17346c73e7238be0fea18f2dc03d7367059e7581f5a662' 
  AND token = 'hLojP1akLXV9kr0EwAWV/Rl7IhSixoYzDlDhOFtB9wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}