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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7606c2c6269ac02ed50f6e5922a282ee36e1ed8a70ebd868a34f00c35e6f25' 
  AND token = 'UCKO4huote2W16FbTu182fWC3u+jFfIWmHyu1jx2C5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}