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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25f2971050a1e7afbb716dca29302738e0a818674f8a26afc9bca589ca60325' 
  AND token = 'o0uQKZd9LALRF0YCrD8f+tk6+z3j6+9NTAalRAmt0+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}