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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da4387203ebdea3489705f0e52b09a07d458a79e4f234df5e0297fe965da423' 
  AND token = 'iP3ICYQAbMRZwB6IAlKuaJ/kKUIAI7w7Cvtd512Kxzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}