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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194ea36f7fc8ac429563e4a467b83ea112da037a78c5ee363b1584fb9f0df19a' 
  AND token = 'yuAc+fSRycZ109uQE+HrZiY3vskoiVu/BU388Vg9kyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}