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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a9468cd5572921518ceb01c048926771525fc8ac9f93ef33d4c4edb3ddaa2e' 
  AND token = 'k6Vyn7rQIrKD0vTRX2qhtQE2Q9i+g4W0VOzFAz2fEUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}