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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46afa8089cbb21c8a74dc766c369002f9c8f5d6d09f3ad639a826c58e516142d' 
  AND token = 'FI7gIlY8pks8c/udJC2w66Oxf3YGtkbq8OIeM7Cv7Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}