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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db517b45f95587f2acd583949c640e2219aa0b0122d49e1282dd096cdd3666e' 
  AND token = 'WB4D52evWP7R+h7ikAMpF/XAMD04SD9GvfZu+kvRwzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}