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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf42bb05b6ea70128d16897a5531f76f1bf96f6641e4c9ecfa605bc3e58b5f1' 
  AND token = '0F9HgpP8Xx+rHq7n42CVtDmpsGnmGEbPoT3ms5zyzZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}