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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437e8e439118dc0161906187b778495d4134a8c9820c7a3642efbe98d0865823' 
  AND token = 'vINleVTM3vcr57yPCvgxoFRgRlHlySbfgd1v8oZOwAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}