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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8151e2fa115221d9949fe32e1eddf4765b6afc26f7bd2cadee04cef77712784' 
  AND token = 'q2K5Se0fqtgkggyyvtgTIDD8kG1ev+CMF0AbIy/6q8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}