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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6e4a3306ccfd1a93942894c6c6a4f73e845697049fb32490b7d5df1860e76e' 
  AND token = 'U/nDhyGx0bNDka4R/9rwQjy3r8A42cKGUQnJym9cfM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}