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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4c7381cd80f69f3537f842cc0d12b9504cf66fed5e4bb813b0d5a0582a8fc6' 
  AND token = 'kOC9kxJ68HW5CRXO0A75v0tC4QmPUIeRIrUaiBG1IuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}