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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5813686d39b11614e1805f78d7e1909dd8d38426f8a0bf9cd1c07b0ddfb8aea8' 
  AND token = 'pz9gr7IP7INQvD8+96XmD8Zl0BlkkbuGB02c9ZuLjd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}