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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cfecbfd1f73e58e7eeee39d18fe6d51aac4c1f4c69cfab8f8065cb87f74ff80' 
  AND token = 'gPNgbzc+q9K4tVQsj+mXRJtHum9CRaXf+4+xbyE1BBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}