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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c73c724488a24d24403b36b0e2bf46cd5f6798a9e878681d7e827cf3f2e04ad' 
  AND token = 'fMJoREgTUtOkEw9NOq0UM411CYbbnWOqmGiIqF9mEQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}